We describe the synthesis of end-functionalized polystyi ems by living anionic polymerization in a micio;tructured reactor via termination by acetal-protected functional epoxidcs Initiation of styiene polymerization by alkyllithium takes place in a nucromixing device with efficient heat and mass transfer properties A newly developed continuous polymerization termination sequence enabled quantitative funetionalization of the living carbanions by nucicophilic displacement with dilfelent, specifically designed ulyeadyl edicts (ethoxy ethyl ulycidyl ether (EEGE). 1,2-isopropyhdenc glyce)'l glycidyl ether (IGG), and trans-2-phenyl-1,3-dioxanc glycidyl ether (PDGE)) Upon acidic hydrolysis the end-capped polystyrenes release multiple hydroxyl groups (2-3) at the chain end Tempel attire and flow rates have been vaned to control molecular weights and to optimize the reaction conditions I'm maximum polymerization and teimmation efficiency The polymers were analyzed in detail using NM R spectroscopy. size exclusion chromatography (SEC), and MALDI-Tor.MS Molecular weights of the sampks prepared ranged between 1800 and 9000 g/mol. For all of the novel termination agents full termination was confir Tied by MALDI-ToF MS The approach presented is applicable for a lame variety of monomers that are polymenzable by carbanionic polymerization