This study addresses the heat transfer in differential scanning calorimetry (DSC) cells during the melting process of an eutectic solution. The energy and entropy equations for two-dimensional transient thermal analysis with associated boundary and initial conditions are solved numerically using a fixed grid numerical model with the finite control volume approach. Proper trends and a good agreement between the results of theoretical modeling and experiment results are obtained. A parametric study with various associated parameters is performed and results are illustrated. (C) 2010 Elsevier B.V. All rights reserved.