\The vapor-liquid equilibrium data for the systems: ethyl palmitate + ethyl stearate at 5332.9 Pa, ethyl palmitate + ethyl oleate at 5332.9 Pa and 9332.6 Pa and ethyl palmitate + ethyl linoleate at 9332.6 Pa were determined by differential scanning calorimetry (DSC). The esters used in this study are the major components of biodiesel obtained from the transesterification of soybean oil with ethanol. According to the results, DSC is appropriate for determining the vapor-liquid equilibrium of binary systems. The binary interaction parameters of the models Wilson. NRTL and UNIQUAC were fitted to the experimental data obtained in this study. Crown Copyright (C) 2010 Published by Elsevier B.V. All rights reserved.