The major objectives of this study are to analytically and experimentally determine the residual resistance factor in the fractured medium based on the polymer solution properties and operational conditions. The parameters considered in this study are the polymer concentration, power law constitutive equation parameter, and salt concentration, sulfonation content of polymer, temperature, and molecular weight of the water soluble polymers which are used in polymer flooding for enhanced oil recovery. The results indicated that residual resistance factor in fractured medium is dependent on the coil overlap parameter and power law equation parameter of polymer. The coil overlap parameter is a dimensionless number consists of intrinsic viscosity and polymer concentration. Since intrinsic viscosity is a function of polymer diameter in medium conditions, to predict the residual resistance factor in fracture medium, an experimental correlation is generated for determination of the molecular diameter of polymer based on polymer molecular weight, temperature, salt concentration, and sulfonation content.