The irreversible photoenhancement of a quantum dot (QD) nanocomposite is demonstrated using UV photo-annealing. The QD nanocomposite consists of a mixture of thermally curable polymer and a QD that is synthesized as a core/multi-shell nanocrystal, CdSe/CdS/CdZnS/ZnS. Exposure under 365-nm UV illumination for 30 min at 70 W surprisingly reveals that the photoluminescence of the QD nanocomposite increases 1.8 times.