We report the synthesis of sepiolite nanofluids via tertiary amine and sulfonate anions. After modified, the sepiolite behaves liquid-like without solvent at room temperature. The content of sepiolite is 25 wt.%. The unique properties of the sepiolite nanofluids and its dispersion have made this promising in the applications as multiphase systems like in common liquids. (C) 2011 Elsevier B. V. All rights reserved.