We have investigated the scope and applicability of Mukherjee's state-specific multireference coupled cluster singles and doubles (Mk-MRCCSD) method on the magnetic interactions in dichloro-, oxo-, and peroxo-bridged binuclear Cu(II) complexes. Several reference orbitals including broken-symmetry natural orbitals (BSNOs) are examined for the Mk-MRCCSD computations. We compare the effective exchange integral (J) values calculated by Mk-MRCCSD with those calculated by conventional complete active space self-consistent field (CASSCF) and MRMP2. The BS methods with approximate spin-projection (AP) method are also performed for comparison. It is found that the Mk-MRCCSD method can be applicable to the prediction of exchange couplings in binuclear copper(II) containing systems. (C) 2011 Elsevier B.V. All rights reserved.