Chemistry Letters, Vol.40, No.1, 90-92, 2011
Inhibitory Effects of Hybrid Liposomes Composed of Phosphatidylcholine and Docosahexaenoic Acid on the Growth of Colon Cancer Cells along with Apoptosis and Differentiation
Novel hybrid liposomes (DMPC/DHA) composed of L-alpha-dimyristoylphosphatidylcholine and docosahexaenoic acid were produced. DMPC/DHA were smaller and more stable than pure DMPC liposomes. It is attractive that DMPC/DHA could remarkably inhibit the growth of human colon cancer HCT116 cells along with apoptosis and differentiation in vitro.