G3-6 beta CD32, which has 32 beta-cyclodextrins functionalized on the surface of a polyamidoamine dendrimer, was prepared as a multivalent host molecule. G3-6 beta CD32 showed selective recognition behaviors for guest polymers. Using guest recognition sites on the surface, a supramolecular bilayer sphere was prepared in aqueous solutions. The molecular recognition properties and structure of G3-6 beta CD32 are reminiscent of a virus structure.