Chemistry Letters, Vol.40, No.10, 1067-1068, 2011
Nickel-catalyzed Heteroannulation of o-Haloanilines with Alkynes
A nickel-catalyzed heteroannulation has been developed where o-haloanilines react with alkynes to afford 2,3-disubstituted indoles. IPr (1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) was found to be an effective ligand for the reaction.