In this study, we analyze the impact of ventilation heat recovery (VHR) on the operation primary energy use in residential buildings. We calculate the operation primary energy use of a case-study apartment building built to conventional and passive house standard, both with and without VHR, and using different end-use heating systems including electric resistance heating, bedrock heat pump and district heating based on combined heat and power (CHP) production. VHR increases the electrical energy used for ventilation and reduces the heat energy used for space heating. Significantly greater primary energy savings is achieved when VHR is used in resistance heated buildings than in district heated buildings. For district heated buildings the primary energy savings are small. VHR systems can give substantial final energy reduction, but the primary energy benefit depends strongly on the type of heat supply system, and also on the amount of electricity used for VHR and the airtightness of buildings. This study shows the importance of considering the interactions between heat supply systems and VHR systems to reduce primary energy use in buildings. (C) 2011 Elsevier B.V. All rights reserved.