This paper deals with the overall operation of a chemical process where continuous and batch units operate jointly. The paper describes a plantwide model predictive controller (MPC) taking into account both continuous manipulated and controlled variables, as well as the ones related to the scheduling of the batch units. The MPC is formulated in a way that avoids the use of integer variables, so that a NLP (nonlinear programming) optimization technique can be applied. Results of the controller operation in simulation are provided.