We report dissociation pressures of propane and ethane simple hydrates in the presence of methanol or ethylene glycol aqueous solutions at different temperatures and various concentrations of inhibitor in aqueous solutions. The equilibrium data were generated using an isochoric pressure-search method. These data are compared with some selected experimental data from the literature on the dissociation conditions of propane and ethane simple hydrates in the presence of pure water to show the inhibition effects of the above-mentioned aqueous solutions. Comparisons are finally made between our experimental data and the corresponding literature data.