Journal of Bioscience and Bioengineering, Vol.111, No.3, 255-258, 2011
Gingival and dermal fibroblasts: Their similarities and differences revealed from gene expression
Gene expression profiles in normal human gingival and dermal fibroblasts were investigated using DNA microarrays. Their fundamental characteristics were almost identical, but 5% of their genes were uniquely expressed. These results help us to choose an optimal cell source for effective fibroblast-based cell therapy that is dependent on differential gene expression profiles. (C) 2010, The Society for Biotechnology, Japan. All rights reserved.