A new vial-in-vial vapour diffusion method for growing single crystals of fully deuterated triglycine sulphate (TGS) has been developed. Single crystals of hydrogenous TGS were also grown for comparison purposes. The crystals have been characterised using x-ray diffraction and differential scanning calorimetry. The phase transition temperature was 334.0 +/- 0.5 K for fully deuterated TGS compared to 322.3 +/- 0.3 K for hydrogenous TGS. These values compare well with the expected T-c. (C) 2011 Elsevier B.V. All rights reserved.