Ratio control for two interacting processes is proposed with a PID feedforward design based on model predictive control (MPC) scheme. At each sampling instant, the MPC control action minimizes a state-dependent performance index associated with a PID-type state vector, thus yielding a PID-type control structure. Compared to the standard MPC formulations with separated single-variable control, such a control action allows one to take into account the non-uniformity of the two process outputs. After reformulating the MPC control law as a PID control law, we provide conditions for prediction horizon and weighting matrices so that the closed-loop control is asymptotically stable, and show the effectiveness of the approach with simulation and experiment results. (C) 2011 Elsevier Ltd. All rights reserved.