Nanoparticles that respond to various chemical and physical stimuli form the basis for various conceivable applications including sensors, chemical logic, biomedical imaging, and therapies. In this work, we demonstrate that the electrostatic and chemical (complexing and gold-thiol bonding) interactions existing in a gold nanoparticle/Zn2+/dithiothreitol-based ternary chemical system is "programmable" and can be utilized to regulate the aggregation and dispersion of nanoparticles via XOR and INHIBIT logics. The resulting solutions alter their colors according to different input combinations because of the well-controlled aggregation or dispersion of plasmonic gold nanoparticles, opening up new possibilities for the developments of advanced sensors and nanobiomedical devices based on the coupling, gating, and signaling of different chemical stimuli.