A group contribution (GC) method is developed to predict the sublimation enthalpy of only any compound constituted with polycyclic aromatic hydrocarbons and/or polycyclic aliphatic rings with an average absolute relative deviation of 8.98% and an average absolute error of 9.22 kJ center dot mol-1. A statistical analysis (ANOVA table) and two validation tests are performed to show the consistency of the method. This GC method can speed up several processes in which it is required the value of the sublimation enthalpy of a solid with these characteristics (pharmaceuticals for instance). However, this method must not be used with inorganic compounds or organic solids with noncyclic structure. (c) 2011 American Institute of Chemical Engineers AIChE J, 2012