Hydrogenolysis of glycerol to 1,3-propanediol in aqueous-phase was investigated over Pt-H4SiW12O40/SiO2 bi-functional catalysts with different H4SiW12O40 (HSiW) loading. Among them, Pt-15HSiW/SiO2 showed superior performance due to the good dispersion of Pt and appropriate acidity. It is found that Bronsted acid sites facilitate to produce 1,3-PDO selectively confirmed by Py-IR. The effects of weight hourly space velocity, reaction temperature and hydrogen pressure were also examined. The optimized Pt-HSiW/SiO2 catalyst showed a 31.4% yield of 1,3-propanediol with glycerol conversion of 81.2% at 200 A degrees C and 6 MPa.