An analytical study on the influence of gas/liquid injection on heat transfer characteristics of two-phase flow boiling of some refrigerant mixtures in horizontal enhanced surface tubing is presented. Correlations were proposed to predict the impact of the gas/liquid injection on the heat transfer characteristics such as average heat transfer coefficient of R-507, R-404A, R-410A and R-407C in two-phase flow boiling inside enhanced surface tubing. The data also revealed that gas/liquid injection is beneficial at certain gas/liquid injection ratios to the heat transfer coefficient depending upon the Reynolds number and the boiling point. It was also evident that the proposed correlations and the experimental data that the gas/liquid injection has significant impact on the heat transfer coefficient. In addition, the proposed correlations were applicable to the entire heat and mass flux, investigated in the present study under gas/liquid injection conditions. The deviation between the experimental and predicted under gas/liquid injection were less than +/- 20, for the majority of data. Copyright (C) 2004 John Wiley Sons, Ltd.