Gelatin, a thermally denatured collagen, forms a temperature-dependent gel, in which the efficiency of the collagen-like triple helix is dependent on temperature. In this study, (proline hydroxyproline glycine) peptides were modified at the dendrimer to produce a type of collagen-mimic dendrimer. These dendrimers worked as a drug carrier with thermosensitive release capabilities and could retain rose bengal molecules stably.