Using TiO2-water nanofluids as the test liquid, pool boiling experiments were carried out to investigate the dependence of the nucleate boiling heat transfer, surface wettability and critical heat flux (CHF) on the boiling time in nanofluids. In the experiments performed at sufficiently high nanoparticle concentrations, the boiling heat transfer first degraded, then improved, and finally reached an equilibrium state. It was hence supposed that the present nanofluids had competing effects to deteriorate and enhance the nucleate boiling heat transfer. As for the surface wettability and CHF, the static contact angle asymptotically decreased whilst the CHF asymptotically increased with an increase in the boiling time. The maximum CHF enhancement measured in the present experiments was 91%, and strong correlation was found between the contact angle and the CHF. Although the boiling time needed to achieve the maximum CHF enhancement was less than a minute at high particle concentrations, a longer time of the order of 1 h was necessary at the lowest particle concentration tested in this work. This experimental result indicated that sufficient attention should be paid to the boiling time effect particularly in industrial applications of nanofluids to emergency cooling. (C) 2012 Elsevier Ltd. All rights reserved.