This paper presents experimentally determined heat transfer coefficients for condensation from a superheated vapor of CO2 and R410A. The superheated vapor was flowed through a smooth horizontal tube with 6.1 mm ID under almost uniform temperature cooling at reduced pressures from 0.55 to 0.95, heat fluxes from 3 to 20 kW m(-2), and superheats from 0 to 40 K. When the tube wall temperature reaches the saturation point, the measured results show that the heat transfer coefficient gradually starts deviating from the values predicted by a correlation valid for single-phase gas cooling. This point identifies the start of condensation from the superheated vapor. The condensation starts earlier at higher heat fluxes because the tube wall temperature reaches the saturation point earlier. The heat transfer coefficient reaches a value predicted by correlations for condensation at a thermodynamic vapor quality of 1. The measured heat transfer coefficient of CO2 is roughly 20-70% higher than that of R410A at the same reduced pressures. This is mainly because the larger latent heat and liquid thermal conductivity of CO2, compared to that of R410A, increase the heat transfer coefficient. (C) 2012 Published by Elsevier Ltd.