We have grown the Sc and Ce doped LiYF4 [ Sc,Ce:LYF] single crystals with various Sc and Ce concentrations and investigated the effects of ionic radius control at Y site by Sc doping on crystal growth and physical properties. All grown Sc,Ce:LYF crystals included the milky and transparent parts and the amount of the milky parts in the crystals was smaller than that of the Ce:LYF crystal. The milky parts were composed of the LYF main phase and YF3 inclusion and in contrast, the transparent parts were a single phase of LYF. The lattice parameters were almost constant for all Sc,Ce:LYF crystals. Full width at half maximum of the XRC for Sc5%Ce5%:LYF crystal was 86.8 arcsec and the effective segregation coefficients of Ce3+ ion in the Sc3%Ce3% and 5c5%Ce5%:LYF crystals were 0.21 and 0.18, respectively. In the transmittance and photoluminescence spectra, no clear effects of Sc co-doping were observed. (C) 2012 Elsevier B.V. All rights reserved.