A new regeneration method using power ultrasound was put forward to overcome the limitations of silica gel in air-conditioning applications, such as high regeneration temperature and low regeneration efficiency. The technical feasibility of the new method was validated experimentally and demonstrated in detail from different sides. The experiments were performed under different regeneration temperatures, i.e. 45 degrees C, 55 degrees C, 65 degrees C and 75 degrees C. The power and frequency of ultrasound applied in this experimental study was set as 40 W and 26 kHz, respectively. The three indicators, including the regeneration degree (RD), enhanced rate of regeneration (ER) and energy-saving rate (ESR), were suggested to evaluate the effect of power ultrasound in the regeneration. The Crank's diffusion model was used for the calculation of the Moisture diffusivity in silica gel, and the Arrhenius equation for the determination of energy activation of moisture desorption on silica gel. The analysis results prove that the introduction of high-intensity ultrasound to the regeneration of silica gel can help to improve the regeneration efficiency and reduce regeneration energy. The benefits should owe to the special 'heating effect' and 'micro-vibration effect caused by power ultrasound that can enhance the moisture diffusivity in silica gel and lower the activation energy of moisture desorption on silica gel. (C) 2009 Elsevier Ltd. All rights reserved.