As a first step towards understanding particle-particle interaction in fluid flows, the motion of two spherical particles settling in close proximity under gravity in Newtonian fluids was investigated experimentally for particle Reynolds numbers ranging from 0.01 to 2000. It was observed that particles repel each other for Re > 0.1 and that the separation distance of settling particles is Reynolds number dependent. At lower Reynolds numbers, i.e. for Re < 0.1, particles settling under gravity do not separate. The orientation preference of two spherical particles was found to be Reynolds number dependent. At higher Reynolds numbers, the line connecting the centres of the two particles is always horizontal, regardless of the way the two particles are launched. At lower Reynolds numbers, however, the particle centreline tends to tilt to an arbitrary angle, even of the two particles are launched in the horizontal plane. Because of the tilt, a side migration of the two particles was found to exist. A linear theory was developed to estimate the side migration velocity. It was found that the maximum side migration velocity is approximately 6% of the vertical settling velocity, in good agreement with the experimental results. Counter-rotating spinning of the two particles was observed and measured in the range of Re = 0-10. Using the linear model, it is possible to estimate the influence of the tilt angle on the rate of rotation at low Reynolds numbers. Dual particles settle faster than a single particle at small Reynolds numbers but not at higher Reynolds numbers, because of particle separation. The variation of particle settling velocity with Reynolds number is presented. An equation which can be used to estimate the influence of tilt angle on particle settling velocity at low Reynolds number is also derived.