In the presence of sucrose, hierarchical mesopores alumina was prepared and used as hydrodesulfurization catalyst support. The pore structure and acidic property of the alumina can be easily controlled by pH value and concentration of precipitator. The physical and chemical properties of catalysts are apparently changed when this novel structure alumina are introduced as support. The interaction between active component and support is decreased. The Mo species are facilely reduced and there are less acid sites on the surface of the catalysts. The unique properties make this catalysts possess higher conversion and desulfurizing ratio for 4,6-DMDBT in this study. (C) 2010 Elsevier B. V. All rights reserved.