The reactions of fullerence[C-60] with 2'-azidoethyl 2,3,4,6-tetra-O-acetyl-alpha-D-mannopyranoside (2a) and 2'-azidoethyl 2,3,4,6-tetra-O-acetyl-beta-D-galactopyranoside (2b) under ultrasonic irradiation cause the cycloaddition of 2'-azidoethyl glycosides to fullerene[C60] and lead to D-glycosyl fullerene[C60] derivatives 3a and 3b, respectively. The glycosyl fullerene[C60] derivatives were characterized by H-1 and C-13 NMR, UV-vis, FAB-MS, FT-IR spectra and were a 1:1 glycoside fullerene [C-60]-adduct. (C) 2007 Published by Elsevier B.V.