Each stack of microstructured stainless steel and aluminum plates was coated and brazed in vacuum. As a supporter of the catalyst, the coating layer was formed by the sol-gel method and anodizing, respectively. Though the number of brazed plates extended to one hundred, the thickness of the coating layer on the coated plate was relatively uniform, and the leakage of assembly was effectively minimized. The critical variables for brazing were both the thickness and shape of filler metal. Consequently, the brazing method had a good resolution for 200 mum, three-dimensional, multilayer structures. Through these results, coating to support catalysts in highly stacked layers by brazing can be applied to microcatalytic heat exchangers where the reaction and heat transfer occur simultaneously.