An advanced dental adhesive system, composed of acrylic monomers and coupling agents, characterized by high tensile bond strength, enhanced durability, and biocompatibility was developed. The adhesive composition is curable chemically (self curing) or by visible light. This adhesive composition can be used for bonding to various substrates such as dentin, enamel, precious and nonprecious alloys, ＇fresh＇ and ＇set＇ amalgam, porcelain, and dental composite. Thus, the developed liquid adhesive composition could be considered as a universal dental adhesive.