| 초록 |
Abstract In this study, we have for the first time applied fractional precipitation with hydrophilic polymer in order to decrease the particle size of the (+)-dihydromyricetin from plant materials. When compared with the case where no hydrophilic polymer was employed, the addition of hydrophilic polymer in fractional precipitation resulted in a considerable decrease in the size of the (+)-dihydromyricetin precipitate. The use of a polymer had an effect on inhibition of precipitate growth compared to prepared particles without polymer. Among the polymers used, HPMC 2910 was the most effective for inhibition of precipitate growth. In addition, a polymer concentration of 0.2 wt% yielded the smallest particle size. However, the particle size increased as the concentration of polymer increased to greater than 0.2 wt%. Acknowledgment This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (Grant Number: 2015016271). |
