| 학회 |
한국화학공학회 |
| 학술대회 |
2007년 가을 (10/26 ~ 10/27, 한국과학기술원) |
| 권호 |
13권 2호, p.2285 |
| 발표분야 |
재료 |
| 제목 |
Silica Nanocontainers by Templating of Magnetic Assemblies for Drug Delivery Vehicles |
| 초록 |
Novel hollow silica nanoparticles (HSNPs) for drug vehicles were synthesized using magnetic assemblies as templates. The cavity core was obtained by injection of hydrochloride and calcination at a high temperature. Doxorubicin was used as a model drug and loaded into the HSNPs. To overcome fast drug release, cationic surface charge-modified and PEGylated HSNPs were prepared and investigated. Sustained drug release from cationic surface charge-modified and PEGylated HSNPs was demonstrated. |
| 저자 |
양재문, 이재원, 강진영, 윤호근, 서진석, 허용민, 함승주
|
| 소속 |
연세대 |
| 키워드 |
silica; nanocontainer; hollow; drug carrier
|
| E-Mail |
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| 원문파일 |
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