| 학회 |
한국공업화학회 |
| 학술대회 |
2010년 봄 (05/13 ~ 05/14, BEXCO(부산)) |
| 권호 |
14권 1호 |
| 발표분야 |
고분자 |
| 제목 |
Surface functionalization of polymeric biosensing plateform by ion irradiation for the detection of target DNA or Antigen |
| 초록 |
In this study, we report on the ion beam-based surface functionalization of a flexible PET film for the fabrication of a biosensor. The PET surface was functionalized by ion beam-induced generation of carboxylic acid. The functionalized PET surface was used for the immobilization of capture molecules, such as probe DNA and alpha-feto protein. The Red-labeled target DNA was hybridized with probe DNA. Primary Ab and Cy3-labeled secondary Ab were bound on AFP. The results showed that the resolved micropatterns of target molecules were formed and their fluorescence intensities was dependent on the concentration of the target DNA and antigen. |
| 저자 |
황인태, 최재학, 국인설, 정찬희, 노영창
|
| 소속 |
한국원자력(연) |
| 키워드 |
Ion beam; PET; Biosensor; Liver cancer; Anthrax toxin
|
| E-Mail |
|
