| 학회 | 한국공업화학회 |
| 학술대회 | 2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center)) |
| 권호 | 24권 1호 |
| 발표분야 | 포스터-생체재료 |
| 제목 | Cancer specific magnetic nanoparticles with hyperthermia and photodynamic therapy |
| 초록 | Magnetic nanoparticles as diagnostic, therapeutic and magnetic resonance imaging (MRI) materials are used in various fields. However, magnetic particles have several huddles. The biggest hurdle is the low amount of drug in the cancerous area. The reason is that most anticancer drugs have low cancer targeting efficiency. We designed magnetic nanoparticles that combine photosensitizers (PS) and polysaccharides (MPPS) to increase cancer target rates and therapeutic effects. Due to the polysaccharide with cancer targeting ability, MPPS has an increased accumulation at the cancer site and has an excellent therapeutic effect. And given laser irradiation and magnetic field, cancer can be treated by hyperthermia and photodynamic therapy (PDT). We confirmed the tumor by MRI. The combination of hyperthermia therapy and PDT has been demonstrated in MPPS with increased therapeutic effects in cancer. MPPS is expected to take cancer treatment to the next level. |
| 저자 | 이태범1, 김경섭2, 나건1 |
| 소속 | 1가톨릭대, 2유타대 |
| 키워드 | Magnetic nanoparticle; Photodynamic therapy; Hyperthermia therapy |
