| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 가을 (10/09 ~ 10/10, 일산킨텍스) |
| 권호 |
33권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Self-Crosslinking Injectable Hydrogels Containing BMP-2 Releasing Gelatin Microspheres |
| 초록 |
A new microsphere-hydrogel composite, composed of BMP-2-loaded gelatin microspheres and self-crosslinking poly(amino acid)-based hydrogels, was developed for a bone-regenerative matrix. The self-crosslinking hydrogel can act as an injectable depot at lesion sites, and incorporated gelatin microspheres, prepared by precision particle fabrication technology, can control the release rate of loaded BMP-2. Microsphere-hydrogel composites described in this work can diversify the class of injectable hydrogel systems for bone tissue engineering. Acknowledgement. This research was supported by a grant (code #: 08K1501-01110) from 'Center for Nanostructured Materials Technology' under '21st Century Frontier R&D Programs' of the Ministry of Education, Science and Technology, Korea. |
| 저자 |
이홍재1, 김경자1, 최형수2, 김계균2, 이상천1
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| 소속 |
1요업(세라믹)기술원, 2Univ. of Illinois |
| 키워드 |
microsphere-hydrogel composite; self-crosslinking; injectable hydrogel; BMP-2 loaded gelatin microsphere; BMP release
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| E-Mail |
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