| 학회 | 한국화학공학회 |
| 학술대회 | 2013년 봄 (04/24 ~ 04/26, 광주 김대중컨벤션센터) |
| 권호 | 19권 1호, p.410 |
| 발표분야 | 생물화공 |
| 제목 | Neurotransmitter detection using Surface-enhanced Raman spectroscopy from PC12 cells |
| 초록 | Dopamine(DA) plays one of important role in central nervous system. PC12 cells are well-known dopaminergic cells in response some chemical treatment. In this study, electrochemical depositon technique was used for gold nanopattern fabrication. PC12 cells were immobilized on nanopatterned ITO(Indium Tin Oxide) substrate. Finally, various chemical agent was treated to PC12 cells and the concentration of DA was successfully monitored by SERS and confirmed by HPLC. Acknowledgement: This research was supported by the Original Technology Research Program for Brain Science through the National Research Foundation of Korea(NRF) funded by the Ministry of Education, Science and Technology (2012-0006592) and by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MEST) (2012-0000163) and by The Nano/Bio Science&Technology Program(M10536090001-05N3609-00110) of the Ministry of Education,Science and Technology(MEST). |
| 저자 | 김경준, Waleed Ahmed El-said, 김태형, 최정우 |
| 소속 | 서강대 |
| 키워드 | SERS; Dopamine; cell chip; biosensor; lable free |
| 원문파일 | 초록 보기 |
