| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
22권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Fabrication and Characterization of PLCL Microsphere Containing Plant Extract |
| 초록 |
Interest in the application of naturally derived medicine in tissue engineering is rapidly growing. Drug delivery system is needed to be exploited for the improvement of the efficacy of drug. This study was intended to develop a polymeric microsphere for the delivery of naturally derived medicine, catechin, for the stimulation of osteoblastic cells. PLCL is a biodegradable and biocompatible polymer suitable for drug carrier. In this study, we synthesized PLCL and used for the fabrication of drug-loaded microsphere. We evaluated the drug loading efficiency and release pattern of the microspheres. Cellular assays displayed the microsphere was cytocompatible and promoted osteoblast proliferation and differentiation. |
| 저자 |
마진쉬엔, 서아인, 류규환, 강혜원, 김경헌, 최선희, 김태연, 이우걸
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| 소속 |
단국대 |
| 키워드 |
PLCL; microsphere; catechin; ; natural medicine
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| E-Mail |
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