화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관)
권호 34권 2호
발표분야 기능성 고분자
제목 Micropatterning of DNAs on the surface of a polymer film functionalized by ion beam-induced graft polymerization for the fabrication of flexible biodevices
초록 In this study, the surface of a flexible polymer substrate was selectively functionalized by an ion beam-induced grafting of acrylic acid. The resulting functionalized substrate was used for the immobilization of probe DNAs, followed by hybridization with Red fluorescence-labeled complimentary DNAs. Well-defined micropatterns of DNAs were obtained, and the fluorescence intensity of the micropatterns was clearly dependent on the concentration of complementary DNAs. This result revealed that flexible biodevices such as biosensors and biochips can be fabricated by using this technology.
저자 황인태1, 김동기1, 정찬희1, 최재학1, 노영창1, 신관우2
소속 1한국원자력(연), 2서강대
키워드 DNA micropattern; surface functionalization; ion beam; polymer
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