화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU))
권호 23권 2호
발표분야 포스터_생체재료
제목 Enhanced osteodifferentiation of MC3T3-E1 preosteoblasts on black phosphorous-coated and -incorporated substrates
초록 Black phosphorus (BP) has attracted many attentions as a two-dimension nanomaterial because of its fascinating physicochemical characteristics. In the present study, two different type of BP-based substrates were designed and their potentials as bone tissue engineering scaffolds were explored. First, BP-coated layers on a slide glass were prepared by meniscus-dragging deposition process. Second, BP-incorporated nanofiber matrices were prepared using electrospinning of PCL to fabricate scaffolds with natural extracellular matrix-mimicking structures. Our results indicated that both BP-coated and incorporated substrates can significantly promote cellular behaviors such as proliferation, and differentiation of MC3T3-E1 preosteoblasts. In conclusion, it is suggested that BP-based substrates can be efficiently utilized for biomedical applications thru coating and electrospinning.
저자 이유빈1, 송수진1, 강문성1, 서희정1, 이현욱2, 김봉주3, 한동욱1
소속 1부산대, 2한국기초과학지원(연), 3서울대
키워드 Black phosphorus; Meniscus-dragging deposition; Electrospinning; Osteodifferentiation; Bone tissue engineering
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