| 학회 |
한국공업화학회 |
| 학술대회 |
2017년 봄 (05/10 ~ 05/12, 광주 김대중컨벤센센터(Kimdaejung Convention Center)) |
| 권호 |
21권 1호 |
| 발표분야 |
우수논문(구두)_석사과정 |
| 제목 |
Biopolymeric Nanocarrier: Targeted Turn On Delivery for Cacner Imaging |
| 초록 |
Nanomedicine based on nanotechnology facilitates the development of both therapeutic and diagnostic agents. Especially, fluorescent-based imaging guidance for tumor resection has recently emerged as a fascinating tool using use of exogenous fluorescent contrast agents with objective and precise information of tumor tissues. However, the most contrast agents inherently cannot offer real-time visual information concerning localization of the tumor because of a lack of cancer targeting property. For selective active tumor targeting, these contrast agents were chemically conjugated with targeting moieties such as antibodies and peptides, but they may not achieve the Food and Drug Administration (FDA) approval due to safety issues. Motivated by this issue, we introduce targeted fluorescent “turn-on” delivery system based on biopolymeric nanocarriers we recently developed without chemical conjugation to the targeting ligand. |
| 저자 |
정윤1, 김가람1, 이병철1, 김상은1, 고원건2, 이강원1
|
| 소속 |
1서울대, 2연세대 |
| 키워드 |
Cancer Imaging; 5-Aminolevulinic acid; Nanocarrier
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| E-Mail |
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