| 학회 | 한국공업화학회 |
| 학술대회 | 2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 | 20권 2호 |
| 발표분야 | 생체재료_포스터 |
| 제목 | Fabrication of alendronic acid-loaded PLCL scaffolds for hard tissue repair |
| 초록 | Caprolactone and L-lactide are basic materials for the preparation of various biomaterials. We synthesized poly(L-lactide-co-caprolactone) (PLCL) using these two monomers. PLCL is a biodegradable polymer and can be readily fabricated into various structures. Alendronic acid is a therapeutic agent widely used for repair of various bone-related diseases. In this study we investigated the effects of incorporation of alendronic acid in PLCL scaffold on physical and biological properties. Various analytical methods, including SEM, EDX, and FT-IR, were utilized to examine the physicochemical properties of the scaffolds. In vitro assessments were performed to analyzed the cellular responses using an osteoblastic cell-line This research was supported by the Ministry of Trade, Industry and Energy(MOTIE), KOREA, through the Education Program for Creative and Industrial Convergence. (Grant Number N0000717) |
| 저자 | 김주승, 김응석, 이정인, 임진익, 이우걸 |
| 소속 | 단국대 |
| 키워드 | tissue; repair; PLCL; alendronate |
