| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
20권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Investigation effect of solution pH on adsorption behavior of proteins on solid/liquid interface |
| 초록 |
Interaction of proteins to material is of critical importance to determine the biocompatibility and consequently the success of implanted materials. The adsorbed protein molecules modulate the subsequent cellular and tissue responses. Therefore, understanding interfacial behavior of protein molecules will be highly useful to anticipate the material performance in biological environment. In this study, we analyzed the adsorption behavior of 3 different globular proteins on calcium phosphate coating under different solution pH. The adsorption kinetics were measured using ATR-FTIR and adsorbed mass was quantified using a protein assay. The infrared spectroscopic analysis revealed that solution pH strongly affect the interfacial behavior of protein molecules and the conformation of protein changes via interaction with surface. |
| 저자 |
김주승, 김응석, 이정인, 임진익, 이우걸
|
| 소속 |
단국대 |
| 키워드 |
proteins; interface; adsorption
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| E-Mail |
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