| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
23권 2호 |
| 발표분야 |
포스터_생체재료 |
| 제목 |
Drug-incorporated Reinforced Chitosan/Collagen Complex Scaffold for the Improvement of Bioactivity |
| 초록 |
An intelligent system to build 3D scaffold as a bone graft can be achieved by incorporating bioactive agents, which deliver drugs to the desired location while avoiding systemic side effects. Among various materials, biodegradable organic materials which can satisfy the prerequisites, i.e. biocompatibility and biodegradability are preferentially considered. In this study, we investigated a feasibility whether the bioactivity of the chitosan (CHN) scaffold could be improved by combining collagen (COL). We investigated whether the degradation and drug release pattern were modulated by COL combination. In addition, we also evaluated the effects of the COL combination on the proliferation and differentiation of osteoblast. Current results illustrated that the biological functionality of CHN scaffold can be considerably improved by the combination of COL. |
| 저자 |
김정헌, 김나연, 남재희, 박이안, 박혜민, 장우재, 이우걸
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| 소속 |
단국대 |
| 키워드 |
CaP; CaP Particle; Alendronate; Chitosan; Collagen; scaffold
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| E-Mail |
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