| 초록 |
Recently, the growth of the elderly population increases the number of patients suffering from osteoporosis. Accordingly, it becomes an immediate need to develop bone grafts for bone replacement. Human bone is composed of 35% organic components, 45% inorganic components, and 20% moisture. Among them, the inorganic component accounts for a large proportion of calcium and phosphate as well as trace elements, such as magnesium, fluorine, sodium, and zinc. In this study, we synthesized phosphate-based inorganic ceramic particles with various chemical states for the use of bone substitutes. The chemical composition, size, surface charge, and degradation pattern are evaluated using SEM, FTIR, zeta potential, and EDX. Biocompatibility of these ceramic particles were examined via cell assays using osteoblastic MG63 cells. |
