| 학회 | 한국공업화학회 |
| 학술대회 | 2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 | 20권 2호 |
| 발표분야 | 생체재료_포스터 |
| 제목 | Drug-combined PCL microspheres in drug delivery system for the improvement of bone regeneration |
| 초록 | Polymeric materials play a crucial role in tissue engineering for the replacement of the damaged bone tissues. In this study, poly(ε-caprolactone) were combined with drug components using activating agents. The efficacy of the drug-combined PCL microspheres were evaluated as a drug delivery carrier. The characteristics of the prepared drug-combined PCL was evaluated in terms of hydrophilicity, chemical state, and drug release ability. The cytocompatibility was examined in terms of adhesion, proliferation, and differentiation of osteoblast. Our results demonstrated that drug-combined PCL can be used for the improvement of bioactivity of biomaterials. This research was supported by the Ministry of Trade, Industry and Energy(MOTIE), KOREA, through the Education Program for Creative and Industrial Convergence. (Grant Number N0000717) |
| 저자 | 정은진, 이우걸, 김주승, 이수희, 성정희 |
| 소속 | 단국대 |
| 키워드 | PCL microsphere; drug delivery; osteoblast; cytocompatibility |
