화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2021년 가을 (11/03 ~ 11/05, 대구 엑스코(EXCO))
권호 25권 2호
발표분야 포스터-생체재료
제목 Nanodiamond as Multimodal Probe for Neuritogenesis and Super-Resolution Imaging
초록 Nanodiamond has been widely applied in biological field such as cell tracking and imaging agent owing to cytocompatibility, bioactivity, and high photobleaching threshold. Recent studies have suggested the neurogenic feasibility of nanodiamond, however, there has been no reports that focus on the multimodal characteristics of nanodiamond which can be used as imaging probe and neuritogenesis-inducing capability. Herein, we explored neuritogenesis-inducing capability of nanodiamond on HT-22 mouse hippocampal neuronal cells and the customized direct stochastic optical reconstruction microscopy (dSTORM) system enabled super high-resolution imaging of neurites. We emphasize the potential of nanodiamond as a multimodal probe capable of regeneration of nerval tissues and high-resolution neural cell imaging.
저자 강문성1, 김재흥1, 장희정1, 이석현1, 조효정1, 김춘태1, 이종호2, Iruthayapandi Selestin Raja1, 김창석1, 한동욱1
소속 1부산대, 2다안코리아
키워드 Nanodiamond; super-resolution imaging; dSTORM; neuritogenesis
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