| 학회 |
한국고분자학회 |
| 학술대회 |
2013년 봄 (04/11 ~ 04/12, 대전컨벤션센터) |
| 권호 |
38권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Effect of Dual Growth Factor-Immobilized Porous Membrane on Bone-to-Tendon Regeneration |
| 초록 |
The bony insertion of soft tissue is described as an enthesis. The enthesis tissue includes collagen fibres that extend from the tendon through two specialized zones of fibrocartilage to anchor into the underlying bone. Tendon injuries are a common problem in both occupational and athletic settings. It is well established that the most failures of tendon are occurred at the bone-to-tendon junction, and the injured tissues typically heal slowly and thus frequently re-rupture with tendon retraction occur. In this study, we fabricated dual growth factor (PDGF-BB for tendon and BMP-2 for bone)-immobilized asymmetrically porous membrane as a polymeric matrix to enhance the bone-to-tendon regeneration. The in vivo animal study to evaluate the bone-to-tendon regeneration potential of the dual growth factor-immobilized asymmetrically porous membrane was investigated using a rat model (This work was supported by a grant from the Korea Ministry of Health and Welfare (Grant No. 2011-A100140)). |
| 저자 |
김태호1, 민현기1, 강준구1, 김중현2, 김해원2, 오세행2, 이진호1
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| 소속 |
1한남대, 2단국대 |
| 키워드 |
Porous Membrane; Dual Growth Factor; Bone-to-Tendon; Regeneration
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| E-Mail |
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