| 학회 |
한국공업화학회 |
| 학술대회 |
2017년 봄 (05/10 ~ 05/12, 광주 김대중컨벤센센터(Kimdaejung Convention Center)) |
| 권호 |
21권 1호 |
| 발표분야 |
생체재료 |
| 제목 |
Cell-laden coronary stents covered with extracellular matrix: In-vitro and in-vivo studies |
| 초록 |
Metal implants have been widely used for the treatment of diseases such as stent and bone anchor and even attracted much attention in wearable devices. However, those have severe disadvantages because of poor biocompatible surface. To improve biocompatibility, we applied a pre-coating of polydopamine (pDA) and fibronectin (FN) to a metal surface (CoCr) and then ultimately constructed fibroblast-derived extracellular matrices (ECMs) through decellularization. The modified surface of CoCr was characterized by SEM, AFM, FT-IR and XPS. Results support that the surface modification with complicated extracellular matrix using pDA and FN can be one of promising approaches for overcoming poor biocompatibility of a metallic devices. |
| 저자 |
정미진1, 박광숙1, 김익환2, 김한별3, 임경섭3, 홍영준3, 한동근1, 정윤기1
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| 소속 |
1한국과학기술(연), 2고려대, 3전남대 |
| 키워드 |
Cell-laden coronary stent; extracellular matrix
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| E-Mail |
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