| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 가을 (10/09 ~ 10/10, 일산킨텍스) |
| 권호 |
33권 2호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Biopolymer-mediated Controllable Bacterial Attachment for Microfluidic Applications |
| 초록 |
We have developed a controllable bacterial attachment method using an elastin-like polypeptide (ELP) and a cell-repellent polymer. The surface of Escherichia coli K-12 was conjugated with ELP and the glass substrate was functionalized with ELP. Cell-repellent polymer was used to make a defined micropattern and prevent nonspecific bacterial attachment. Reversible bacterial attachment and detachment was achieved by controlling the phase transition of ELP molecules. This method can be applied to the bacterial flagella-powered applications including mixing, pumping, and transporting. The common problems in bacterial microfluidic applications, especially bacterial lysis and contamination caused by bacterial differentiation, can be overcome by this method. |
| 저자 |
이종환1, 나경아1, 정재연1, 박수범1, 김명진1, 허필우2, 현진호1
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| 소속 |
1서울대, 2한국기계(연) |
| 키워드 |
elastin-like polypeptide; bacteria; microfluidics
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| E-Mail |
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