| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터) |
| 권호 |
44권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Functionalized Polycaprolactone-based 3D Printing Scaffold for Enhanced Bone Regeneration |
| 초록 |
Segmental bone defects can occur in patients suffering from trauma, infection or tumor resection and bone defects need intervention therapy to achieve restoration with sufficient recovery. However, traditional bone grafts cannot completely meet the clinical requirements. To compensate these limitations, many scaffolds based on biomaterials have been developed. In recent years, 3D printing scaffolds have gained increasing interest as an alternative for bone reconstruction. However, their insufficient biological properties for bone regeneration still remained as a critical problem. In this study, we fabricated a growth factor-loaded PCL 3D printing scaffold with leaf-stacked structure which can allow sustained release of the growth factor as well as improved cell adhesiveness. The morphology, mechanical properties, growth factor release behavior and cell adhesiveness/proliferation/differentiation of 3D printing scaffold with leaf-stacked structure were investigated. |
| 저자 |
김민지1, 노하연1, 박수아2, 변준호3, 이진호4, 오세행1
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| 소속 |
1단국대, 2한국기계(연), 3경상대, 4한남대 |
| 키워드 |
3D printing; Bone regeneration; Growth factor; BMP-2; Tissue engineering
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| E-Mail |
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